Listeria. This lantibiotic is the first natural preservative found to kill gram-negative bacteria, typically the harmful kind.
“It’s aimed at protecting foods from a broad range of bugs that cause disease,” said Dan O’Sullivan, professor of food science and nutrition. “Of the natural preservatives, it has a broader umbrella of bugs that it can protect against.”
The lantibiotic could be used to prevent harmful bacteria in meats, processed cheeses, egg and dairy products, canned foods, seafood, salad dressing, fermented beverages and many other foods. In addition to food-safety benefits, lantibiotics are easy to digest, nontoxic, do not induce allergies and are difficult for dangerous bacteria to develop resistance against.
O’Sullivan discovered the lantibiotic by chance, while researching the genome of bacteria. He then collaborated with Ju-Hoon Lee, a U of M graduate student, to continue the research. The U of M’s Office for Technology Commercialization is currently seeking a licensee for the technology.
“Salmonellaburden has increased more dramatically than any other foodborne illness,” said Shaun Kennedy, director of the National Center for Food Protection and Defense. “The largest recall in 2010 for food contamination was eggs contaminated with salmonella.”
SalmonellaandE. coli, both gram-negative bacteria, account for more than half of all food recalls in the US.Salmonellacontributes to an estimated 28 percent of more than 3,000 deaths related to foodborne illness each year, according to the Centers for Disease Control and Prevention.
“At this time, it is not available for sale. Dr. O'Sullivan has proven its inhibitory function and is in the process of scaling it up for industrial use,” a spokesperson told MEATPOULTRY.com.