Research yields potential Campy vaccine
TUCKER, Ga. – Researchers at the USDA Richard B. Russell Agricultural Research Center in Athens, Ga., have identified a potential vaccine for Campylobacter
, the USPOULTRY Foundation reported. The Foundation funded the project.
Researchers purified proteins from Campylobacter
and tested them for potential use as vaccines. One particular protein, FliD, showed particular promise.
"We found that this protein is present in all of our 21 C. jejuni
isolates and is immunogenic in broilers," according to the researchers' report. "Therefore, this protein will be an excellent candidate for further evaluation as a vaccine to reduce Campylobacter
in poultry. In addition, antibodies to this protein may be used for as a tool to monitor the Campylobacter
status during poultry production."
The researchers also found that broiler sera reacted to a variety of Campylobacter
proteins, demonstrating that chickens had been exposed to or infected with Campylobacter
and consequently developed antibodies against it. The study showed antibodies against the FliD protein were widespread in poultry populations.
"Therefore, control of Campylobacter
exposure through vaccination of chickens is a logical approach to Campylobacter
control, and the FliD protein is a good vaccine candidate," the report stated. "Further studies must be done to evaluate the use of this protein by in ovo
application to determine its potential practical use and efficacy."